I take route 7 up to Sugarbush. It is slower than going out to 87 via 4 to 149 (especially if I cut over from 100 via 73 to 30) but there are more places to stop to eat along route 7. And alternatively, I can hop on 22 once I hit NY and take the Taconic south to avoid the tolls. Both ways end up being similar in time but Route 7 to 4 to 100 generally has much better pavement than dealing with the potholes (or should i say craters) on 73.
I-87-149-4-22A-73-100 is my weekly route to Sugarbush. Only place on 73 that really has a lot of potholes is in the Brandon gap area but it really never bothered me much. I could see 7 being better though if you want places to eat along the way. My usual goal is to eat when I get up to Sugarbush though. If I leave late and know that won't happen, then I stop in Glens Falls. On the way home I'll either eat before I leave or stop in Brandon to eat.